Breaking the Code

As a researcher, you will work with Dr. Strahl to investigate biological processes using budding yeast as a model organism. Not only is this organism fairly simple to grow and study, but what is learned is directly applicable to how enzymes operate in human cells, which is relevant as many of these enzymes have been associated with various human diseases including cancer.

The genetic blueprint of life occurs in the form of DNA, which is packaged within the nucleus of each cell in our body. DNA packaging, and its organization in the nucleus, is regulated by a class of proteins called histones. These proteins create individual histone-DNA complexes, referred to as nucleosomes, which are further folded into higher-order chromatin structures that are poorly defined. Dr. Strahl’s lab seeks to understand these structures through applying a combination of genetic, biochemical and high-throughput proteomic approaches.

As part of your summer externship, you will learn about genetics, biochemistry, model systems and research collaboration as you work alongside Dr. Strahl and his team. Armed with new knowledge and access to experts in the field, you will develop curriculum that integrates your experience with this innovative and exciting research while maintaining alignment with your content standards. This experience will allow you to return to the classroom equipped to inspire the next generation of research scientists as they engage in relevant, hands-on experiences developed throughout your externship.